Cryptococcus laurentii endogenous endophthalmitis post COVID-19 infection.
Muthugaduru Jagadish DeepaChitta MegharajSantosh PatilPadmaja Kumari RaniPublished in: BMJ case reports (2022)
A man in mid-50s presented with progressive blurred vision in his left eye for over 6 weeks. He was a known diabetic with history of COVID-19 pneumonia treated with steroids and remdesivir. He had pyelonephritis and urinary culture grown Klebsiella He was referred as a case of non-resolving vitreous haemorrhage. Visual acuity (VA) was hand movements with fundus showing dense vitritis. He underwent pars plana vitrectomy, vitreous biopsy with intraocular antibiotics (imipenem) suspecting as a case of endogenous bacterial endophthalmitis. Vitreous biopsy did not yield organisms on the smear/culture. The patient's condition worsened with perception of light and fundus showing dense vitritis with discrete yellowish white deposits on the surface of the retina. A repeat vitreous biopsy done along with intravitreal injection of voriconazole (suspecting fungal aetiology) grown fungal colonies and the organism was identified as Cryptococcus laurentii At 4-month follow-up, the VA improved to 6/24.
Keyphrases
- diabetic retinopathy
- ultrasound guided
- fine needle aspiration
- cataract surgery
- optical coherence tomography
- coronavirus disease
- sars cov
- multiple sclerosis
- type diabetes
- pulmonary tuberculosis
- vascular endothelial growth factor
- case report
- cell wall
- mycobacterium tuberculosis
- extracorporeal membrane oxygenation
- optic nerve