Exploring NT-proBNP, syndecan-1, and cytokines as biomarkers for transfusion-associated circulatory overload in a critically ill patient population receiving a single-unit red blood cell transfusion.
Esther B BulleBritt BlankenRobert B KlandermanLisa van ManenNicole P JuffermansAlexander P. J. VlaarPublished in: Transfusion (2023)
NT-proBNP was not associated with TACO in this critically ill patient population. Interestingly, levels of syndecan-1 were increased in TACO patients at baseline. More research is needed to clarify this association and its possibilities as a biomarker to predict patients at risk for TACO.