TSP1-CD47-SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium.

Yukai LiuMing-Qing LiChunyan WeiLingli TangYanran ShengYuyin LiuDa-Jin LiDing DingJianping QiuXiao-Yong Zhu

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

TSP1-CD47-SIRPα signaling pathway not only improves the viability of NESCs per se but also promotes their survival circumstances by affecting the function of macrophages and VECs, which are mutually reinforcing and jointly promote the development of endometriosis.

Keyphrases

signaling pathway
free survival
pi k akt
nk cells
oxidative stress
induced apoptosis