ICOSL Stimulation by ICOS-Fc Accelerates Cutaneous Wound Healing In Vivo.
Ian StoppaCasimiro Luca GigliottiNausicaa ClementeDeepika PanthamChiara DianzaniChiara MongeChiara PuricelliRoberta RollaSalvatore SuttiFilippo RenóRenzo BoldoriniElena BoggioUmberto DianzaniPublished in: International journal of molecular sciences (2022)
These data show that the ICOS/ICOSL network cooperates in tissue repair, and that triggering of ICOSL by ICOS-Fc improves cutaneous wound healing by increasing angiogenesis and recruitment of reparative macrophages.