Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker.
Divyanshu DubeyThomas KryzerYong GuoBenjamin D S ClarksonJohn C ChevilleBrian A CostelloBradley C LeibovichAlicia Algeciras-SchimnichClaudia LucchinnettiM Bakri HammamiAndrew M KnightCharles HoweVanda A LennonAndrew McKeonSean J PittockPublished in: Annals of neurology (2021)
LUZP4-IgG represents a novel serological biomarker of PNS and has high predictive value for germ cell tumors. The demonstrated antigen-specific T-cell responses support a CD8+ T-cell-mediated cytotoxic paraneoplastic and antitumor potential. ANN NEUROL 2021;89:1001-1010.
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