Ultra-hypofractionated whole breast adjuvant radiotherapy in the real-world setting: single experience with 271 elderly/frail patients treated with 3D and IMRT technique.

Maria Alessia ZerellaSamantha DicuonzoSamuele FrassoniMattia ZaffaroniMarianna Alessandra GerardiAnna MorraDamaris Patricia RojasSimona ArculeoLuca BergamaschiCristiana FodorFrancesca EmiroConsiglia PiccoloVincenzo BagnardiFederica CattaniViviana GalimbertiPaolo VeronesiRoberto OrecchiaMaria Cristina LeonardiBarbara Alicja Jereczek-Fossa

Published in: Journal of cancer research and clinical oncology (2022)

Weekly ultra-hypofractionated whole breast RT seems feasible and effective. Toxicity was mild, local control was acceptable, and overall survival was 97.8% at 3 years. Rates of severe toxicity were reduced with the IMRT technique.

Keyphrases

radiation therapy
early stage
high resolution
oxidative stress
community dwelling
locally advanced
radiation induced
middle aged
early onset
free survival
drug induced
rectal cancer
mass spectrometry