Trait Conscientiousness predicts rate of brain atrophy in multiple sclerosis.

Tom A FuchsRalph Hb BenedictGregory WildingCurtis WojcikDejan JakimovskiNiels BergslandDeepa P RamasamyBianca Weinstock-GuttmanRobert ZivadinovMichael G Dwyer

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2019)

We observed significant age and Conscientiousness by time-from-baseline interactions indicating that younger age and higher Conscientiousness are associated with reduced progression of brain atrophy.

Keyphrases

multiple sclerosis
white matter
resting state
functional connectivity
cerebral ischemia
genome wide
brain injury
gene expression