Impact of pregnancy on progression of preclinical autoimmune disorders: a prospective cohort study.

Fausta BeneventiCamilla BellingeriIrene De MaggioChiara CavagnoliAnna BoschettiSerena GiannicoMaria Paola PandolfiCarolina SpadaCarlomaurizio MontecuccoArsenio Spinillo

Published in: Rheumatology (Oxford, England) (2022)

Among women with suspected autoimmune disease during pregnancy, additional viable pregnancies and diagnosis of preeclampsia were independently associated with an increased rate of progression to definite rheumatic disorder. Hormonal modifications associated with pregnancy could worse preclinical rheumatic disorders favouring their progression to a defined autoimmune disease.

Keyphrases

pregnancy outcomes
preterm birth
multiple sclerosis
rheumatoid arthritis
pregnant women
mesenchymal stem cells