Exploring the relationship between DNA methylation age measures and psychoneurological symptoms in women with early-stage breast cancer.

Gee Su YangKai YangMichael T WeaverDebra Lynch KellySusan G DorseyColleen K Jackson-CookDebra E Lyon

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2022)

Our findings suggest DNAm age and AA may be associated with PN symptoms over the course of cancer treatment and survivorship. Some PN symptoms may be amenable to preventive interventions targeted to epigenetic clocks that influence aging-associated processes.

Keyphrases

dna methylation
early stage
gene expression
sleep quality
physical activity
cancer therapy
squamous cell carcinoma
drug delivery
lymph node