Limitations of ion mobility spectrometry-mass spectrometry for the relative quantification of architectural isomeric polymers: A case study.
Romain LiénardQuentin DuezScott M GraysonPascal GerbauxOlivier CoulembierJulien De WinterPublished in: Rapid communications in mass spectrometry : RCM (2020)
These results were explained by an ionization efficiency issue. This work underlines some intrinsic limitations when using IMS-MS in the context of the relative quantification of isomers having different ionization efficiencies. Nevertheless, the linear-to-cyclic ratio can be roughly estimated by this method.