Anaphylactic and nonanaphylactic reactions to SARS-CoV-2 vaccines: a systematic review and meta-analysis.
Saad AlhumaidAbbas Al MutairZainab Al AlawiAli A RabaanRaghavendra TirupathiMohammed A AlomariAqeel S AlshakhesAbeer M AlshawiGasmelseed Y AhmedHassan M AlmusabehTariq T AlghareebAbdulaziz A AlghuwainemZainab A AlsulaimanMohammed A AlabdulmuhsinEmad A AlBuwaidiAmjad K Bu DukhiHani N MuftiManaf Al-QahtaniKuldeep DhamaJaffar A Al-TawfiqAwad Al-OmariPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2021)
The prevalence of COVID-19 mRNA vaccine-associated anaphylaxis is very low; and nonanaphylactic reactions occur at higher rate, however, cutaneous reactions are largely self-limited. Both anaphylactic and nonanaphylactic reactions should not discourage vaccination.