The impact of smoking and smoking cessation on disease outcomes in ulcerative colitis: a nationwide population-based study.

Jonathan Blackwell Sonia Saxena Christopher Alexakis Alex Bottle Elizabeth Cecil Azeem Majeed Richard C G Pollok

Published in: Alimentary pharmacology & therapeutics (2019)

Smokers and never-smokers with UC have similar outcomes with respect to flares, thiopurine use, corticosteroid dependency, hospitalisation and colectomy. Smoking cessation was not associated with worse disease course. The risks associated with smoking outweigh any benefits. UC patients should be counselled against smoking.

Keyphrases

smoking cessation
replacement therapy
end stage renal disease
ulcerative colitis
chronic kidney disease
peritoneal dialysis
prognostic factors
type diabetes
adipose tissue
metabolic syndrome
patient reported outcomes
risk assessment
glycemic control
human health
weight loss