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Microfluidic acoustic sawtooth metasurfaces for patterning and separation using traveling surface acoustic waves.

Mingxin XuPeter V S LeeDavid John Collins
Published in: Lab on a chip (2021)
We demonstrate a sawtooth-based metasurface approach for flexibly orienting acoustic fields in a microfluidic device driven by surface acoustic waves (SAW), where sub-wavelength channel features can be used to arbitrarily steer acoustic fringes in a microchannel. Compared to other acoustofluidic methods, only a single travelling wave is used, the fluidic pressure field is decoupled from the fluid domain's shape, and steerable pressure fields are a function of a simply constructed polydimethylsiloxane (PDMS) metasurface shape. Our results are relevant to microfluidic applications including the patterning, concentration, focusing, and separation of microparticles and cells.
Keyphrases
  • high throughput
  • circulating tumor cells
  • single cell
  • liquid chromatography
  • label free
  • wastewater treatment
  • mass spectrometry
  • cell fate
  • endoplasmic reticulum stress