Phytochemicals of Rhus spp. as Potential Inhibitors of the SARS-CoV-2 Main Protease: Molecular Docking and Drug-Likeness Study.

Yousery E SherifSami A GabrNasser M HosnyAhmad H AlghadirRayan Alansari

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

Six phenolic compounds of Rhus spp. are proposed for synthesis as potential inhibitors against Mpro and have potential for the treatment of COVID-19. These results encourage further in vitro and in vivo investigations of the proposed ligands and research on the preventive use of Rhus spp. against SARS-CoV-2.

Keyphrases

sars cov
molecular docking
respiratory syndrome coronavirus
molecular dynamics simulations
human health
emergency department
climate change
combination therapy