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Molecularly imprinted polymers as a selective sorbent for forensic applications in biological samples-a review.

Juliana Barreto FerreiraClebson de Jesus MacrinoLaíse Aparecida Fonseca DinaliJoão Francisco Allochio FilhoCamilla Fonseca SilvaKeyller Bastos BorgesWanderson Romão
Published in: Analytical and bioanalytical chemistry (2021)
Molecularly imprinted polymers (MIP) consist of a molecular recognition technology with applicability in different areas, including forensic chemistry. Among the forensic applications, the use of MIP in biological fluid analysis has gained prominence. Biological fluids are complex samples that generally require a pre-treatment to eliminate interfering agents to improve the results of the analyses. In this review, we address the development of this molecular imprinting technology over the years, highlighting the forensic applications of molecularly imprinted polymers in biological sample preparation for analysis of stimulant drugs such as cocaine, amphetamines, and nicotine.
Keyphrases
  • molecularly imprinted
  • solid phase extraction
  • tandem mass spectrometry