Pediatric lung transplantation and end of life care in cystic fibrosis: Barriers and successful strategies.
Elisabeth DellonSamuel B GoldfarbDon HayesGregory S SawickiJoanne WolfeDebra BoyerPublished in: Pediatric pulmonology (2017)
Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their caregivers are often simultaneously preparing for lung transplantation and end of life. In this article, we will discuss the current barriers to success in pediatric CF lung transplantation as well as approaches to end of life care in this population.
Keyphrases
- cystic fibrosis
- extracorporeal membrane oxygenation
- end stage renal disease
- pseudomonas aeruginosa
- newly diagnosed
- ejection fraction
- palliative care
- lung function
- prognostic factors
- adipose tissue
- stem cells
- type diabetes
- bone marrow
- metabolic syndrome
- chronic obstructive pulmonary disease
- patient reported outcomes
- weight loss
- smoking cessation