Recombinant Human FSH Treatment Outcomes in Five Boys With Severe Congenital Hypogonadotropic Hypogonadism.

Ella KohvaHanna HuopioMatti Hero Päivi J MiettinenKirsi VaaralahtiVirpi Sidoroff Jorma Toppari Taneli Raivio

Published in: Journal of the Endocrine Society (2018)

Spermatogenesis can be induced with gonadotropins even in boys with HH who have extremely small testes, and despite low-dose T treatment given in early puberty. Induction of puberty with gonadotropins allows preservation of fertility.

Keyphrases

recombinant human
low dose
drug induced
high glucose
replacement therapy
high dose
diabetic rats
early onset
oxidative stress
combination therapy