ATF2/BAP1 Axis Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage via P53 Pathway.

Qi Tian Chengli Liu Jianming Liao Guijun Wang Wenrui Han Xiao-Xing Xiong Zhibiao Chen Lijuan Gu Mingchang Li

Published in: Stroke (2024)

Our results suggest that the neuronal ATF2/BAP1 axis exerts a brain-damaging effect by modulating P53 activity and stability and may be a novel therapeutic target for SAH.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
endoplasmic reticulum stress
brain injury
transcription factor
blood brain barrier
multiple sclerosis
cell proliferation