Pulmonary large cell neuroendocrine carcinoma with adrenal oligorecurrence successfully treated by adrenalectomy.

Hiroki Sato Motoko TachiharaTatsunori KiriuMasatsugu YamamotoYugo TanakaYoshihiro Nishimura

Published in: Respirology case reports (2020)

A 63-year-old man suspected of having lung cancer underwent right upper lobectomy and was diagnosed with large cell neuroendocrine carcinoma (LCNEC). Eleven months after surgery, he developed an oligorecurrence in the adrenal gland and underwent left adrenalectomy. The specimen revealed LCNEC metastasis. Forty-one months after surgery, enlargement of a lesion near the surgical site was seen. Biopsy showed LCNEC metastasis and he is currently undergoing radiotherapy for the recurrent lesion. We report a case of LCNEC with adrenal gland oligorecurrence treated by adrenalectomy, which led to long-term survival.

Keyphrases

single cell
cell therapy
radiation therapy
pulmonary hypertension
stem cells
locally advanced
radiation induced
ultrasound guided
mesenchymal stem cells
newly diagnosed