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Real-world clinical outcomes following treatment intensification with GLP-1 RA, OADs or insulin in patients with type 2 diabetes on two oral agents (PATHWAY 2-OADs).

Cyrus V DesouzaAndreas R KirkKamal K ManglaMichael L WoldenIldiko Lingvay
Published in: BMJ open diabetes research & care (2021)
In propensity score-matched cohorts, GLP-1 RAs demonstrated significant benefits for both glycemic control and weight management over additional OAD(s) or insulin, respectively, indicating that they may represent the optimal choice at these points in the treatment pathway.
Keyphrases
  • glycemic control
  • type diabetes
  • weight loss
  • blood glucose
  • rheumatoid arthritis
  • body mass index
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • body weight