Comparative effectiveness of common therapies for Wilson disease: A systematic review and meta-analysis of controlled studies.
Christian Appenzeller-HerzogTim MathesMarlies L S HeeresKarl Heinz WeissRoderick H J HouwenHannah EwaldPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
There are some indications that zinc is safer than D-penicillamine therapy while being similarly effective in preventing or reducing hepatic or neurological WD symptoms. Study quality was low warranting cautious interpretation of our findings.