Nonactivated Aziridine Synthesis by Intermolecular Polarity-Mismatched Carboamination of Unactivated Alkenes with Unactivated Alkyl Halides.
Linlin WuLei LiYao ZhaoJiacheng RuiYing ZhanLing ZhangRizhi ChenJianrong Steve ZhouChenjie ZhuXiaojin WuPublished in: Organic letters (2024)
A general intermolecular polarity-mismatched carboamination reaction of unactivated alkenes with unactivated alkyl halides has been developed. A series of nonactivated alkyl-substituted aziridines were constructed in exclusive regioselectivity. The dual polarity-mismatched mechanism might be involved.