Fucoxanthin, the constituent of Laminaria japonica, triggers AMPK-mediated cytoprotection and autophagy in hepatocytes under oxidative stress.

Eun Jeong JangSang Chan KimJu-Hee LeeJong Rok LeeIl Kon KimSu Youn BaekYoung-Woo Kim

Published in: BMC complementary and alternative medicine (2018)

These findings suggest that FX have the function of being a hepatic protectant against oxidative damages through the AMPK pathway for the control of autophagy.

Keyphrases

oxidative stress
cell death
endoplasmic reticulum stress
skeletal muscle
signaling pathway
induced apoptosis
dna damage
diabetic rats
protein kinase