Generation of IL-2-Fc-antibody conjugates by click chemistry.

Lindsay WilliamsLin LiPaul J YazakiPatty WongAaron MillerTeresa HongErasmus K PokuSupriyo Bhattacharya John E ShivelyMaciej Kujawski

Published in: Biotechnology journal (2023)

The production of antibody targeted IL-2 therapy via a click chemistry approach is feasible with comparable activity to genetically produced ICKs with the added advantage of multiplexing with other monoclonal antibodies. This article is protected by copyright. All rights reserved.

Keyphrases

cancer therapy
drug discovery
drug delivery
mesenchymal stem cells
stem cells
smoking cessation