CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.

Jiasheng ChenYuxin LinShukai ZhengQingshan ChenShijie TangXiaoping Zhong

Published in: Journal of translational medicine (2023)

Our results suggest that the overexpression of CBX3 promotes ccRCC advancement through PI3K/AKT activation and even immunological dysregulation, making it a potentially viable and beneficial therapeutic target.

Keyphrases

pi k akt
cell proliferation
signaling pathway
cell cycle arrest
clear cell
transcription factor
cell death