Pre-diagnostic and post-diagnostic psychopharmacological treatment of 16 288 patients with bipolar disorder.
Ole Köhler-ForsbergChristiane GasseFredrik HieronymusLiselotte PetersenRune H ChristensenAndrew A NierenbergSøren Dinesen ØstergaardPublished in: Bipolar disorders (2020)
The increased use of two or more antidepressants suggests more focus on bipolar disorder as a differential diagnosis to treatment-resistant unipolar depression. The decreased use of lithium (consistent with international trends) and the prevalent use of antidepressants without overlapping treatment with a drug with mood-stabilizing properties are concerning.