A novel competition ELISA for the rapid quantification of SARS-CoV-2 neutralizing antibodies in convalescent plasma.

Christophe P StoveCaro VerbruggheRosalie DevlooIsabelle DebruyneDorien De ClippelLeen Van HeddegemKristin Van AschVéronique Van GaverMiek VanbrabantAn MuylaertVeerle CompernolleHendrik B Feys

Published in: Transfusion (2021)

The competition ELISA screens for neutralizing antibodies in CCP by competition for just a single epitope. It exerts a sensitivity of 61% with no false identifications. These ELISA designs can be used for epitope mapping or for selection of CCP.

Keyphrases

monoclonal antibody
sars cov
dengue virus
high resolution
high throughput
respiratory syndrome coronavirus
high density
dna methylation
quantum dots