The effect of angiotensin converting enzyme gene insertion/deletion polymorphism on anthropometric and biochemical parameters among hypertension patients: A case-control study from Northwest Ethiopia.
Tsegaye Adane BirhanMeseret Derbew MollaKibur Hunie TesfaPublished in: PloS one (2023)
The DD genotype of the ACE gene polymorphism was found to have a significant association with high blood pressure and blood glucose levels in the study population. Advanced studies with a considerable sample size may be needed to utilize the ACE genotype as a biomarker for the early detection of hypertension-related complications.
Keyphrases
- angiotensin converting enzyme
- blood pressure
- blood glucose
- angiotensin ii
- end stage renal disease
- hypertensive patients
- heart rate
- newly diagnosed
- ejection fraction
- prognostic factors
- chronic kidney disease
- body composition
- peritoneal dialysis
- type diabetes
- glycemic control
- genome wide
- dna methylation
- copy number
- patient reported outcomes
- skeletal muscle
- gene expression
- genome wide identification