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Diurnal variation of salivary oxidative stress marker 8-hydroxyguanine.

Sintaroo WatanabeYuya KawasakiKazuaki Kawai
Published in: Genes and environment : the official journal of the Japanese Environmental Mutagen Society (2019)
The 8-OHGua levels in saliva exhibited diurnal variation. The levels were higher at the time of awakening. At this point, the daytime levels of salivary 8-OHGua may be appropriate for evaluating the individual oxidative stress status. Further study is needed for understanding and utilizing the 8-OHGua levels at the time of awakening.
Keyphrases
  • oxidative stress
  • dna damage
  • obstructive sleep apnea
  • physical activity
  • signaling pathway