Pathological Downstaging and Survival Outcomes Associated with Neoadjuvant Chemotherapy for Variant Histology Muscle Invasive Bladder Cancer.

Nicholas H ChakiryanDa David JiangKyle A GillisElizabeth GreenAli HajiranLee HugarLogan ZempJingsong ZhangRohit JainJad ChahoudMichael PochBrandon J ManleyRoger LiWade SextonScott M Gilbert

Published in: The Journal of urology (2021)

Neoadjuvant chemotherapy was associated with pathological downstaging for all MIBC histological variants, with improved OS for patients with UC, sarcomatoid variant UC and neuroendocrine carcinoma.

Keyphrases

neoadjuvant chemotherapy
muscle invasive bladder cancer
locally advanced
lymph node
sentinel lymph node
copy number
squamous cell carcinoma
gene expression
radiation therapy