Comparative study of granulomatosis with polyangiitis subsets according to ANCA status: data from the French Vasculitis Study Group Registry.

Xavier PuechalMichele IudiciChristian PagnouxPascal CohenMohamed HamidouAchille AoubaFrançois LifermannMarc RuivardOlivier AumaîtreBernard BonnotteFrancois MaurierThomas Le GallouEric HachullaAlexandre KarrasChahéra KhouatraNoémie Jourde-ChicheJean-François ViallardClaire Blanchard-DelaunayPascal GodmerAlain Le QuellecThomas QuéméneurClaire de MoreuilLuc MouthonBenjamin TerrierLoïc Guillevinnull null

Published in: RMD open (2022)

Based on this large cohort, ANCA-negative versus ANCA-positive patients more frequently had limited disease but similar RFS and OS. MPO-ANCA-positive patients had similar RFS but lower OS due to their older age. PR3-ANCA-positive GPA patients' RFS was lower than those of the two other subsets combined but that difference did not persist when comparing only PR3 versus MPO-ANCA-positive patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
physical activity
machine learning
patient reported outcomes
big data
deep learning