Developmental outcomes in children exposed to Zika virus in utero from a Brazilian urban slum cohort study.
Juan P Aguilar TiconaNivison NeryJoseph B Ladines-LimClaudia GambrahGielson Almeida SacramentoBruno de Paula FreitasJoseane BouzonJamary Oliveira-FilhoAna BorjaHaritha AdhikarlaMagelda MontoyaAthena ChinElsio A WunderVerena BallalaiCarina VieiraRubens BelfortAntonio R P AlmeidaMitermayer Galvão Dos ReisEva HarrisAlbert I KoFederico CostaPublished in: PLoS neglected tropical diseases (2021)
A significant proportion of children exposed in utero to ZIKV developed mild cognitive delay and auditory behavioral abnormalities even in the absence of gross birth defects such as microcephaly and other neurodevelopmental domains. Furthermore, our findings suggest that over half of these abnormalities could be attributed to intrauterine ZIKV exposure.