Loading enhances glucose uptake in muscles, bones, and bone marrow of lower extremities in humans.

Jakob BellmanTanja SjörosDaniel HäggErika Atencio HerreJanina HietaOlli EskolaKirsi LaitinenPirjo NuutilaJohn-Olov JanssonPer-Anders JanssonKari KalliokoskiAnne RoivainenClaes Ohlsson

Published in: The Journal of clinical endocrinology and metabolism (2024)

Increased weight-bearing loading enhances GU in muscles, cortical bone, and bone marrow of the exposed lower extremities. This could be interpreted as increased local energy demand in bone and muscle caused by increased loading. The physiological importance of the increased local GU by static loading remains to be determined.

Keyphrases

bone marrow
soft tissue
mesenchymal stem cells
bone mineral density
physical activity
type diabetes
metabolic syndrome
body composition
body weight