Vitamin B12 Catalyzed Atom Transfer Radical Addition.

Keith Ó ProinsiasAgnieszka JackowskaKatarzyna RadzewiczMaciej GiedykDorota Gryko

Published in: Organic letters (2017)

Vitamin B12, a natural Co-complex, catalyzes atom transfer radical addition (ATRA) of organic halides to olefins. The established conditions were found to be very selective, with atom transfer radical polymerization (ATRP) occurring only in the case of acrylates.

Keyphrases

electron transfer
molecular dynamics
water soluble