Potential Hypoglycaemic and Antiobesity Effects of Senna italica Leaf Acetone Extract.

R O Malematja Victor P BaglaI NjanjeVusi G MbazimaK W PoopediLeseilane J Mampuru Matlou P Mokgotho

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

The acetone leaf extract of S. italica stimulates glucose uptake through the PI3K-dependent pathway and can serve as a source of therapeutic agent for the downregulation of obesity-associated adipokines in obesity and antiglycation agents.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
oxidative stress
cell proliferation
signaling pathway
adipose tissue
skeletal muscle
blood glucose
body mass index
blood pressure
risk assessment