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Adverse Event Profile for Nanoparticle Albumin-Bound Paclitaxel Compared With Solvent-Based Taxanes in Solid-Organ Tumors: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Fei HeJiaxuan LiuXin ShenZijing WangQiao LiGuohui Li
Published in: The Annals of pharmacotherapy (2021)
Nab-paclitaxel increased the risk of hematologic and non-hematologic AEs in general, but anaphylaxis was less common, and the recovery duration of neurotoxicity was shorter. Weekly administration of nab-paclitaxel at a lower dosage provided better tolerance.
Keyphrases
  • advanced non small cell lung cancer
  • chemotherapy induced
  • emergency department
  • clinical trial
  • tyrosine kinase
  • drug induced