Discovery of plasma proteins associated with ventricular fibrillation during first ST-elevation myocardial infarction via proteomics.

Niels Kjær StampeMaud Eline OttenheijmLylia DriciNicolai J Wewer AlbrechtsenAnnelaura Bach NielsenChristina Christoffersen Peder Emil Warming Thomas EngstrømBo Gregers WinkelReza Jabbari Jacob Tfelt Hansen Charlotte Glinge

Published in: European heart journal. Acute cardiovascular care (2023)

VF due to first STEMI was significantly associated with two up-regulated proteins (ACTBL2 and F13A1), suggesting that they may represent novel underlying molecular VF mechanisms. Further research is needed to determine whether these proteins are predictive biomarkers or acute phase response proteins to VF during acute ischemia.

Keyphrases

st elevation myocardial infarction
percutaneous coronary intervention
heart failure
small molecule
mass spectrometry
liver failure
high throughput
intensive care unit
hepatitis b virus
single cell
drug induced
aortic dissection