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Parasitic encephalitis caused by Stephanurus dentatus in a pig in Brazil.

Robert G S PradoChris H GardinerMárcio A O MouraGerson B E GonzalezMarcos D DuarteTiago F S SantosPedro S BezerraValiria Duarte CerqueiraAlessandra S AmaralGabriela Riet-Correa
Published in: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2021)
A pig was in left lateral recumbency with limb spasticity, accentuated prostration, and strabismus, and was euthanized. During autopsy, yellowing of the leptomeninges at the ventral pons to medulla oblongata was noted. In the cerebellar peduncles, there was a focally extensive black-to-yellow area at the level of the vestibular nuclei. Histologic examination revealed a cross-section of a nematode larva, consistent with Stephanurus dentatus, bordered by edema and marked infiltration of mononuclear cells, plasma cells, and a few eosinophils. Vacuolation of the neuropil, with rare gitter cells and axonal spheroids, was also observed. We diagnosed parasitic encephalitis caused by S. dentatus migration based on the pathology findings and characterization of the parasite.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • spinal cord injury
  • oxidative stress
  • minimally invasive
  • peripheral blood
  • cell proliferation
  • children with cerebral palsy
  • life cycle