Nuclear hypochromasia: Shedding light on the "lightness" of high-grade urothelial carcinoma.

TPS and use of hyperchromasia as a feature of HGUC is affirmed. However, hypochromasia, while not diagnostic in isolation, is present in a sub-set of patients with HGUC (10.2%) and should be considered as a variance noted in the nuclei of HGUC.