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Cohort profile for the MASTERMIND study: using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with type 2 diabetes.

Lauren R RodgersMichael N WeedonWilliam E HenleyAndrew T HattersleyBeverley M Shields
Published in: BMJ open (2017)
Findings from studies using these data will help inform future treatment plans and guidelines. Additional data are added with updates from CPRD. This will increase the numbers of patients on newer medications and add more data on those already receiving treatment. There are several ongoing studies investigating different hypotheses regarding differential response to treatment and progression of diabetes. For side effects, links to Hospital Episode Statistics data, where severe events such as hypoglycaemia will be recorded, will also be explored.
Keyphrases
  • type diabetes
  • clinical practice
  • cardiovascular disease
  • healthcare
  • big data
  • end stage renal disease
  • newly diagnosed
  • combination therapy
  • ejection fraction
  • skeletal muscle
  • adipose tissue
  • peritoneal dialysis