Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer.

Krishan KumarDeepak KanojiaDavid J BentremRosa F HwangJonathan P ButcharSusheela TridandapaniHidayatullah G Munshi

Published in: Cells (2023)

Our results demonstrate the pro-tumorigenic role of HYAL1 and identify the role of BRD2 in the regulation of HYAL1 in PDAC. Overall, these data enhance our understanding of the role and regulation of HYAL1 and provide the rationale for targeting HYAL1 in PDAC.

Keyphrases

cancer therapy
electronic health record
clinical trial
big data
anti inflammatory
drug delivery
hyaluronic acid
recombinant human
artificial intelligence