Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-κB/p65 Signaling in Chronic Radiculitis Rats.
Junnan WangMingyi WuXiaowen LinYun LiZhi Jian FuPublished in: Pain research & management (2018)
Intrathecal administration of low-concentration oxygen/ozone alleviated mechanical allodynia and attenuated radiculitis, likely by a PDE2A-cGMP/cAMP-NF-κB/p65 signaling pathway in chronic radiculitis rats.
Keyphrases
- signaling pathway
- pi k akt
- protein kinase
- nitric oxide
- neuropathic pain
- lps induced
- hydrogen peroxide
- particulate matter
- epithelial mesenchymal transition
- induced apoptosis
- binding protein
- oxidative stress
- nuclear factor
- spinal cord injury
- drug induced
- cell proliferation
- immune response
- inflammatory response
- air pollution
- smoking cessation