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Detection of SARS-CoV-2 RNA in Upper Respiratory Swap Samples by Pooling Method

Yeşim Tuyji TokMert Ahmet KuskucuHazal ErdemDevrim SarıbalSeda Salman YılmazOkan Kadir NohutRidvan KaraaliI Lker İnanç BalkanBilgül MeteÖmer Fehmi TabakGokhan AygunKenan Midilli
Published in: Balkan medical journal (2021)
The pooling strategy is an effective approach to extend the impact of limited testing resources and reagents available in certain periods of the COVID-19 pandemic. Testing by pooling samples requires improvement of RNA extraction methods and careful monitoring of RT-PCR test sensitivity to avoid missing low-positive entities. Therefore, based on the prevalence of COVID-19 in their regions, laboratories should conduct their own validation of pooling studies for RNA extraction and amplification methods they use.
Keyphrases
  • sars cov
  • nucleic acid
  • coronavirus disease
  • respiratory syndrome coronavirus
  • risk factors
  • real time pcr
  • label free
  • respiratory tract