Characterization Of Chromosome-Mediated Colistin Resistance In Escherichia coli Isolates From Livestock In Korea.
Shukho KimJung Hwa WooNayeong KimMi Hyun KimSe Yeon KimJoo Hee SonDong Chan MoonSuk-Kyung LimMin-Sang ShinJe-Chul LeePublished in: Infection and drug resistance (2019)
Our results suggest that the mechanism underlying chromosome-mediated colistin resistance remain to be discovered in E. coli. Selective pressure of colistin in vitro induced the same genetic mutations associated with colistin resistance in vivo. Efforts to reduce colistin consumption in livestock should be redoubled, to prevent the occurrence of colistin-resistant E. coli strains.