Ultrasensitive detection of oncogenic human papillomavirus in oropharyngeal tissue swabs.

Andre IsaacMorris KostiukHan ZhangCameron LindsayFawaz MakkiDaniel A O'ConnellJeffrey R HarrisDavid W J CoteHadi SeikalyVincent L Biron

Published in: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (2017)

Oropharyngeal swabs analyzed by ddPCR is a quantitative, rapid, and effective method for minimally invasive oncogenic HPV detection. This assay represents the most sensitive and accurate mode of HPV detection in OPSCC without a tissue biopsy in the available literature.

Keyphrases

loop mediated isothermal amplification
label free
minimally invasive
real time pcr
high grade
systematic review
high resolution
transcription factor
high throughput
sensitive detection
quantum dots
tandem mass spectrometry