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The SafeBoosC II randomized trial: treatment guided by near-infrared spectroscopy reduces cerebral hypoxia without changing early biomarkers of brain injury.

Anne M PlomgaardWim van OeverenTue H PetersenThomas AlderliestenTopun AustinFrank van BelManon J N L BendersOlivier ClarisEugene DempseyAxel R FranzMonica FumagalliChristian GluudCornelia HagmannSimon Hyttel-SorensenPetra LemmersAdelina PellicerGerhard PichlerPer WinkelGorm Greisen
Published in: Pediatric research (2015)
Treatment guided by NIRS reduced the cerebral burden of hypoxia without affecting EEG or the selected blood biomarkers.
Keyphrases
  • brain injury
  • subarachnoid hemorrhage
  • cerebral ischemia
  • endothelial cells
  • functional connectivity
  • risk factors