Four Biomarkers Linked to Activation of Cluster of Differentiation 8-Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure.
Mike A LeonisAlexander G MiethkeLin FeiSean MaynorCatherine A ChapinJacob J H BleesingEstella M AlonsoRobert H Squiresnull nullPublished in: Hepatology (Baltimore, Md.) (2021)
Four circulating T-lymphocyte activation markers identify a subgroup of PALF participants with evidence of immune activation associated with a distinct clinical phenotype and liver transplantation; these biomarkers may identify PALF participants eligible for future clinical trials of early targeted immunosuppression.