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Comparative evaluation of small molecules reported to be inhibitors of Staphylococcus aureus biofilm formation.

Mara J CampbellKaren E BeenkenHorace J SpencerBina JayanaHana HesterGyan S SahukhalMohamed O ElasriMark S Smeltzer
Published in: Microbiology spectrum (2023)
. Of the 19 compounds compared using this method, many had no impact on biofilm formation under these conditions. Indeed, only one proved effective at limiting biofilm formation without also inhibiting growth.
Keyphrases
  • biofilm formation
  • staphylococcus aureus
  • pseudomonas aeruginosa
  • candida albicans
  • escherichia coli
  • signaling pathway
  • methicillin resistant staphylococcus aureus
  • cystic fibrosis