Mechanisms of Innate Immune Injury in Arrhythmogenic Cardiomyopathy.
Stephen P ChelkoVinay PennaMorgan EngelMaicon Landim-VieiraElisa N CannonKory LavineJeffrey E SaffitzPublished in: bioRxiv : the preprint server for biology (2023)
We have uncovered a therapeutically targetable innate immune mechanism regulating myocardial injury and cardiac function in a clinically relevant mouse model of Arrhythmogenic Cardiomyopathy (ACM).