BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.

Published in: Journal of assisted reproduction and genetics (2023)

BNIP3-induced autophagy is crucial in primordial follicle loss during OTT procedure, and BNIP3 is a potential therapeutic target for primordial follicle loss after OTT.

Keyphrases

germ cell
cell death
endoplasmic reticulum stress
oxidative stress
signaling pathway
diabetic rats
cell proliferation
minimally invasive
stem cells